Patients with Coronavirus disease 2019 (COVID-19) often have elevations in markers of liver injury, particularly serum aspartate transaminase (AST) and alanine transaminase (ALT). Such alterations may affect the AST/ALT ratio (De Ritis ratio) and, potentially, clinical outcomes. We conducted an updated systematic review and meta-analysis of the association between the De Ritis ratio and COVID.. De Ritis ratio (DRR) was first described by Fernando De Ritis in 1957 to differentiate viral hepatitis from other icteric and anicteric liver diseases 8. Aspartate aminotransferase (AST) is predominantly expressed in mitochondria and is abundantly present in many organs including the liver, kidney, brain, heart, and skeletal musculature.
LABConsult Limites de Decisão O Índice de De Ritis para Lesões Hepáticas

Table 4 from The effect of AST/ALT (De Ritis) ratio on survival and its relation to tumor

N = 3755Mean values for GOT (AST), GPT (ALT) and the de Ritis quotient... Download Scientific

Pairwise correlation between the De Ritis ratio (AST/ALT) and age,... Download Scientific Diagram

Comparison of the Impact of the De Ritis Ratio on Prognosis in Breast... Download Scientific

Viruses Free FullText The Elevated De Ritis Ratio on Admission Is Independently Associated

Table 1 from A Retrospective Analysis of the De Ritis Ratio in Muscle Invasive Bladder Cancer

Distribution of Deritis ratio in ALD and NAFLD. Download Scientific Diagram

Forest plots of the association between the De Ritis ratio and... Download Scientific Diagram

Diagnostics Free FullText Using Second Measurement of De Ritis Ratio to Improve Mortality

Life Free FullText An Updated Systematic Review and MetaAnalysis of the Association

PPT ALTERACIÓN DE PRUEBAS DE FUNCIÓN HEPÁTICA PowerPoint Presentation ID224207

Comparison of clinicopathological variables according to De Ritis ratio... Download Table

Life Free FullText An Updated Systematic Review and MetaAnalysis of the Association

Life Free FullText An Updated Systematic Review and MetaAnalysis of the Association

PPT Chapter 8 Diagnostic Enzymology And Other Biochemical Markers Of Organ Damage PowerPoint

Forest plots of the association between the De Ritis ratio and... Download Scientific Diagram

PPT Chapter 8 Diagnostic Enzymology And Other Biochemical Markers Of Organ Damage PowerPoint

The adjusted hazard ratio for ALT (A), AST (B) and the De Ritis ratio... Download Scientific

Viruses Free FullText The Elevated De Ritis Ratio on Admission Is Independently Associated
Abstract: Background: Abnormal liver function tests can identify severe cardiopulmonary failure. The aspartate transaminase/alanine transaminase (AST/ALT) ratio, or the De Ritis ratio, is commonly used to evaluate acute liver damage. However, its prognostic value in pulmonary embolism (PE) is unknown.. De Ritis ratio was not independently associated with RFS in multivariate analyses. During the follow up, a total of 198 (66.2%) patients died, including 173 (57.9%) from BC, 5‐year CSS was 45.8%.