With postexposure prophylaxis, comprised of HepB vaccine and hepatitis B immune globulin (HBIG) at birth, followed by completion of the HepB vaccine series, 0.7% through 1.1% of infants develop infection; infants born to mothers with high viral loads are at greatest risk for infection despite receipt of HepB vaccine and HBIG.. The CDC recommends the hepatitis B vaccine for all infants, all children or adolescents younger than 19 years of age who have not been vaccinated, all adults ages 19 through 59 years and adults age 60 years or older with risk factors for hepatitis B infection. Get hepatitis B vaccine information Schedule a hepatitis B vaccination

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What is hepatitis B? Hepatitis B is a highly contagious, serious liver disease caused by the hepatitis B virus. It is spread through contact with the blood or other body fluids of an infected person, including contact with objects that could have blood or body fluids on them such as toothbrushes and razors. The hepatitis B virus can cause:. The hepatitis B vaccine is given as an injection into the upper arm or thigh. You need at least 3 doses of the vaccine to give you the best protection from hepatitis B. There's usually a month gap between each dose, but sometimes 3 doses can be given within 21 days (with a 4th dose at 12 months) if you need faster protection.